Phase separation–based HTS identifies cobimetinib as aYAP- TEAD inhibitor that suppresses hyperactivatedYAP- induced cancer progression
The Hippo signaling pathway prevents unchecked cell gro …
Publications
To cleave or not to cleave: a systemic evaluation of DSS versus DSSO for cross-linking mass spectrometry analysis
Cross-linking mass spectrometry is a powerful method fo …
Enantioselective Deaminative crosscoupling of amino acid derivatives and alkylzirconocenes
The enantioselective constructionof C(sp3)-rich archite …
Total synthesis of natural products based on hydrogenation of aromatic rings
Haoxiang Wu and Xiangbing Qi Arenes and heteroarenes ar …
Radical Ring Expansion Catalyzed by an α-Ketoglutarate-Dependent Dioxygenase in the Biosynthesis of Tropolones
Mingjie Liu, Jiawang Liu, Songlin Bai, Ziang Chen, Yali …
Cp*Ir(III)-Catalyzed Asymmetric Tandem Intramolecular Aziridination/Aza-Semipinacol Rearrangement of Alkenyl 1,4,2-Dioxazol-5-one
Mengbo Wu, Yuanzhen Xu, Songlin Bai, Qiqi An, Jiacheng …
Structure-Based Optimization of TBK1 Inhibitors
Wenxuan Sun, Yuting Xie, Qiancheng Xia, Yuanxun Wang, X …
Total synthesis of (±)-3-demethoxyerythratidinone via Tf2O-promoted cascade reaction of enaminone
Mingliang Lou, Xiaolei Liu, Shoule Han, Songlin Bai and …
Dissecting caspase-2-mediated cell death: from intrinsic PIDDosome activation to chemical modulation
Mengxue Zeng, Kun Wang, Qingcui Wu, Jingjin Ding, Dan X …
Enantioselective Decarboxylative C(sp3)-C(sp3) Cross-Coupling of Aliphatic Redox-Active Esters with gem-Borazirconocene Alkanes
Jing Wang, Songlin Bai, Chao Yang and Xiangbing Qi Asym …