Unlocking the secrets to human NTCP structure
Xiangbing Qi* and Wenhui Li* Sodium taurocholate co-tra …
分类： Medicinal chemistry
BAFinder: A software for unknown bile acid identification using accurate mass LC-MS/MS in positive and negative modes
Yan Ma,* Yang Cao, Xiaocui Song, Yuanying Zhang, Jing L …
Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction via Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine
Daojiang Yan, Kunya Wang, Songlin Bai, Bingyu Liu, Jian …
An improved auxin-inducible degron system for fission yeast
Xiao-Ran Zhang, Lei Zhao, Fang Suo, Yadong Gao, Qingcui …
Structure of PDE3A–SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells
Jie Chen, Nan Liu, Yinpin Huang, Yuanxun Wang, Yuxing S …
5-IP7: a GPCR messenger mediating muscarinic control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis
Xiaozhe Zhang, Na Li, Jun Zhang, Yanshen Zhang, Xiaoli …
Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11
Zilin Li, Wang Liu, Jiaqi Fu, Sen Cheng, Yue Xu, Zhiqia …
Design of Dimeric Bile Acid Derivatives as Potent and Selective Human NTCP Inhibitors
Yang Liu, Lei Zhang, Huan Yan, Zhiqiang Wang, Guoliang …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
Lu Lv, Peihao Chen, Longzhi Cao, Yamei Li, Zhi Zeng, Yu …
An alkaloid initiates phosphodiesterase 3A–schlafen 12 dependent apoptosis without affecting the phosphodiesterase activity
Youwei Ai, Haibing He, Peihao Chen, Bo Yan, Wenbin Zhan …