A thiazole-derived oridonin analog exhibits antitumor activity by directly and allosterically inhibiting STAT3
Xiaofei Shen 1, Lin Zhao 1, Peihao Chen, … Continued
A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity
Cheng-Yang Wu, Santhosh Satapati, Wenjun … Continued
Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice
Cheng-Yang Wu, Shih-Chia Tso, Jacinta L. … Continued
a hybridiza-tionchain-reaction-based method for amplifying immunosignals
Rui Lin, Qiru Feng, Peng Li, Ping Zhou, … Continued
In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery
Yanli Wang, Yuze Sun, Ran Cao, Dan Liu, … Continued
Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors
Shih-Chia Tso, Mingliang Lou, Cheng-Yang … Continued
Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals
Yaling Wu, Dingbin Tang, Na Liu, Wei Xio … Continued