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A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp 3 C-H arylation

2021-12-13 by admin

Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfe …

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A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity

2021-12-10 by admin

Cheng-Yang Wu, Santhosh Satapati, Wenjun Gui, Richard M …

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Development of the Vinylogous Pictet–Spengler Cyclization and Total Synthesis of (±)-Lundurine A

2021-12-10 by admin

Aaron Nash, Xiangbing Qi, Pradip Maity, Kyle Owens, and …

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A hybridization-chain-reaction-based method for amplifying immunosignals

2021-12-13 by admin

Rui Lin, Qiru Feng, Peng Li, Ping Zhou, Ruiyu Wang, Zhe …

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A general strategy for synthesis of cyclophanebraced peptide macrocycles via palladiumcatalysed intramolecular sp3 C−H arylation

2021-04-28 by admin

Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfe …

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Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice

2021-04-28 by admin

Cheng-Yang Wu, Shih-Chia Tso, Jacinta L. Chuang, Wen-Ju …

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a hybridiza-tionchain-reaction-based method for amplifying immunosignals

2021-04-28 by admin

Rui Lin, Qiru Feng, Peng Li, Ping Zhou, Ruiyu Wang, Zhe …

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In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery

2021-04-28 by admin

Yanli Wang, Yuze Sun, Ran Cao, Dan Liu, Yuting Xie, Li …

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Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors

2021-04-28 by admin

Shih-Chia Tso, Mingliang Lou, Cheng-Yang Wu, Wen-Jun Gu …

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Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals

2021-04-28 by admin

Yaling Wu, Dingbin Tang, Na Liu, Wei Xiong, Huanwei Hua …

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News

  • Unlocking the secrets to human NTCP structure
  • BAFinder: A software for unknown bile acid identification using accurate mass LC-MS/MS in positive and negative modes
  • Asymmetric Total Syntheses of Strychnos Alkaloids via Selective Fischer Indolization
  • Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction via Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine
  • Expeditious and Efficient ortho-Selective Trifluoromethane-sulfonylation of Arylhydroxylamines
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